HYPERKINETIC PULMONARY HYPERTENSION
Since pulmonary artery pressure is the product of pulmonary vascular resistance and cardiac output, any increase in pulmonary blood flow is invariably associated with an increase in pulmonary artery pressure. If the increased flow is sustained,as in intracardiac shunts, anatomical changes occur in the pulmonary vessels (vascular remodeling) which increase vascular resistance and further increase pulmonary artery pressure, causing the pulmonary hypertension to persist even after the initial stimulus is corrected. Remodeling consists initially of the muscularization and hypertrophy of previously unmuscularized small arteries, followed by medial hypertrophy and intimal proliferation in the larger pulmonary arteries. Both of these changes are reversible if the pulmonary hypertension is reduced. However, persistently high pressures produce permanent obstructive changes such as necrotizing arteritis and complex dilatations known as plexiform lesions.
- Pulmonary Vasculitis
- CAUSES OF PULMONARY HYPERTENSION
- CLINICAL FEATURES OF PULMONARY HYPERTENSION
- TREATMENT
- EFFECTS OF PULMONARY HYPERTENSION ON PULMONARY FUNCTION
- OBLITERATIVE OR OBSTRUCTIVE PULMONARY HYPERTENSION
- HYPERKINETIC PULMONARY HYPERTENSION
- Miscellaneous
- SPECIFIC ENTITIES - DISEASES WITH KFiOWIi ETIOLOGIES -
- Other Clearly Extrinsic Causes of Diffuse Infiltrative Lung Disease
- Sarcoidosis
- CLINICAL MANIFESTATIONS
- Hypersensitivity Pneumonitis
- EMBOLIC DISEASE
- Pulmonary Hemorrhagic Disorders
- POSTCAPILLARY PULMONARY HYPERTENSION
- DIFFUSE LUNG DISEASE OF UNKNOWN ETIOLOGY
- DIFFUSE INFILTRATIVE DISEASES OF THE LUNG
- PHYSIOLOGICAL EFFECTS OF PULMONARY HYPERTENSION ON CARDIAC FUNCTION
- Pulmonary Infiltrates with Eosinophilia PIE
- Idiopathic Pulmonary Fibrosis